Dystonia in corticobasal degeneration: a review of the literature on 404 pathologically proven cases.
Identifieur interne : 000E04 ( Main/Exploration ); précédent : 000E03; suivant : 000E05Dystonia in corticobasal degeneration: a review of the literature on 404 pathologically proven cases.
Auteurs : Maria Stamelou [Royaume-Uni] ; Araceli Alonso-Canovas ; Kailash P. BhatiaSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2012.
English descriptors
- KwdEn :
- MESH :
- complications : Basal Ganglia Diseases, Neurodegenerative Diseases.
- etiology : Dystonia.
- pathology : Basal Ganglia, Basal Ganglia Diseases, Cerebral Cortex, Dystonia, Neurodegenerative Diseases.
- Humans.
Abstract
Dystonia is considered one of the classical features of corticobasal degeneration and is reported in up to 83% in clinical, not pathologically confirmed, series. Here, we aimed to establish the frequency and the clinical characteristics of dystonia in CBD by reviewing the literature on 404 pathologically proven cases. Further, we aimed to identify the frequency and characteristics of dystonia in all described phenotypes with CBD pathology. Dystonia was present in only 37.5% of the 296 cases with adequate information. The majority of the cases with dystonia presented with a corticobasal syndrome, and dystonia occurred in the first 2 years from disease onset, affecting the upper limb. In cases with dystonia that presented with a "dementia" phenotype, dystonia tended to appear later in the disease course and to more affect the cervical region and the face. With regard to the distribution of the phenotypes, fifty-four percent of 374 cases presented as corticobasal syndrome, 15% as frontotemporal dementia, and 10.7% as progressive supranuclear palsy. Dystonia and myoclonus were present in about half of all cases with corticobasal syndrome, implying that these features may not be as frequent in corticobasal syndrome as are akinetic-rigid syndrome and apraxia (100% and 86.3%, respectively). Dystonia and myoclonus almost co-occurred in our analysis, suggesting a possible association. In conclusion, despite dystonia being an inclusion criterion in all sets of clinical criteria for corticobasal degeneration, this was present in only one third of the pathologically proven cases presented here. More accurate characterization of dystonia in corticobasal degeneration would be of importance for clinical diagnosis and development of treatment strategies.
DOI: 10.1002/mds.24992
PubMed: 22550031
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000D84
- to stream PubMed, to step Curation: 000D84
- to stream PubMed, to step Checkpoint: 000E44
- to stream Ncbi, to step Merge: 003646
- to stream Ncbi, to step Curation: 003646
- to stream Ncbi, to step Checkpoint: 003646
- to stream Main, to step Merge: 000E34
- to stream Main, to step Curation: 000E04
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Dystonia in corticobasal degeneration: a review of the literature on 404 pathologically proven cases.</title><author><name sortKey="Stamelou, Maria" sort="Stamelou, Maria" uniqKey="Stamelou M" first="Maria" last="Stamelou">Maria Stamelou</name><affiliation wicri:level="3"><nlm:affiliation>Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London, United Kingdom. m.stamelou@ucl.ac.uk</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Alonso Canovas, Araceli" sort="Alonso Canovas, Araceli" uniqKey="Alonso Canovas A" first="Araceli" last="Alonso-Canovas">Araceli Alonso-Canovas</name></author><author><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P" last="Bhatia">Kailash P. Bhatia</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="doi">10.1002/mds.24992</idno><idno type="RBID">pubmed:22550031</idno><idno type="pmid">22550031</idno><idno type="wicri:Area/PubMed/Corpus">000D84</idno><idno type="wicri:Area/PubMed/Curation">000D84</idno><idno type="wicri:Area/PubMed/Checkpoint">000E44</idno><idno type="wicri:Area/Ncbi/Merge">003646</idno><idno type="wicri:Area/Ncbi/Curation">003646</idno><idno type="wicri:Area/Ncbi/Checkpoint">003646</idno><idno type="wicri:Area/Main/Merge">000E34</idno><idno type="wicri:Area/Main/Curation">000E04</idno><idno type="wicri:Area/Main/Exploration">000E04</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Dystonia in corticobasal degeneration: a review of the literature on 404 pathologically proven cases.</title><author><name sortKey="Stamelou, Maria" sort="Stamelou, Maria" uniqKey="Stamelou M" first="Maria" last="Stamelou">Maria Stamelou</name><affiliation wicri:level="3"><nlm:affiliation>Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London, United Kingdom. m.stamelou@ucl.ac.uk</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Alonso Canovas, Araceli" sort="Alonso Canovas, Araceli" uniqKey="Alonso Canovas A" first="Araceli" last="Alonso-Canovas">Araceli Alonso-Canovas</name></author><author><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P" last="Bhatia">Kailash P. Bhatia</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Basal Ganglia (pathology)</term><term>Basal Ganglia Diseases (complications)</term><term>Basal Ganglia Diseases (pathology)</term><term>Cerebral Cortex (pathology)</term><term>Dystonia (etiology)</term><term>Dystonia (pathology)</term><term>Humans</term><term>Neurodegenerative Diseases (complications)</term><term>Neurodegenerative Diseases (pathology)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Basal Ganglia Diseases</term><term>Neurodegenerative Diseases</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dystonia</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Basal Ganglia</term><term>Basal Ganglia Diseases</term><term>Cerebral Cortex</term><term>Dystonia</term><term>Neurodegenerative Diseases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Dystonia is considered one of the classical features of corticobasal degeneration and is reported in up to 83% in clinical, not pathologically confirmed, series. Here, we aimed to establish the frequency and the clinical characteristics of dystonia in CBD by reviewing the literature on 404 pathologically proven cases. Further, we aimed to identify the frequency and characteristics of dystonia in all described phenotypes with CBD pathology. Dystonia was present in only 37.5% of the 296 cases with adequate information. The majority of the cases with dystonia presented with a corticobasal syndrome, and dystonia occurred in the first 2 years from disease onset, affecting the upper limb. In cases with dystonia that presented with a "dementia" phenotype, dystonia tended to appear later in the disease course and to more affect the cervical region and the face. With regard to the distribution of the phenotypes, fifty-four percent of 374 cases presented as corticobasal syndrome, 15% as frontotemporal dementia, and 10.7% as progressive supranuclear palsy. Dystonia and myoclonus were present in about half of all cases with corticobasal syndrome, implying that these features may not be as frequent in corticobasal syndrome as are akinetic-rigid syndrome and apraxia (100% and 86.3%, respectively). Dystonia and myoclonus almost co-occurred in our analysis, suggesting a possible association. In conclusion, despite dystonia being an inclusion criterion in all sets of clinical criteria for corticobasal degeneration, this was present in only one third of the pathologically proven cases presented here. More accurate characterization of dystonia in corticobasal degeneration would be of importance for clinical diagnosis and development of treatment strategies.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement></list><tree><noCountry><name sortKey="Alonso Canovas, Araceli" sort="Alonso Canovas, Araceli" uniqKey="Alonso Canovas A" first="Araceli" last="Alonso-Canovas">Araceli Alonso-Canovas</name><name sortKey="Bhatia, Kailash P" sort="Bhatia, Kailash P" uniqKey="Bhatia K" first="Kailash P" last="Bhatia">Kailash P. Bhatia</name></noCountry><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Stamelou, Maria" sort="Stamelou, Maria" uniqKey="Stamelou M" first="Maria" last="Stamelou">Maria Stamelou</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Santé/explor/MovDisordV3/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E04 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000E04 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Santé
|area= MovDisordV3
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:22550031
|texte= Dystonia in corticobasal degeneration: a review of the literature on 404 pathologically proven cases.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:22550031" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a MovDisordV3
| This area was generated with Dilib version V0.6.23. |  |